YUCARLAB investigates the cellular, molecular, and structural mechanisms underlying reproductive competence, ovarian function, early embryo development, and reproductive disease models. We provides an integrated experimental platform combining reproductive biology, developmental biology, histology, molecular analysis, cell culture, and quantitative imaging. Our laboratory offers expertise in mouse embryo culture, ovarian and uterine tissue analysis, immunofluorescence-based marker evaluation, reproductive disease models, and image-driven quantitative assessment.
Current Research
Ovarian Microenvironment and Fibrosis
We investigate how ovarian stromal remodeling, extracellular matrix alterations, inflammatory signaling, oxidative stress, and cellular stress pathways contribute to ovarian dysfunction, follicular loss, and reproductive aging. Our work aims to identify molecular and structural signatures that may inform future therapeutic strategies for preserving ovarian function.
Early Embryo Development and Cell Fate
Our embryo research focuses on the molecular mechanisms that regulate early lineage specification, trophectoderm formation, inner cell mass identity, cell–cell communication, and developmental competence during the preimplantation period.
Molecular Signaling in Reproductive Function
We explore key signaling pathways, including Hippo/YAP, mTOR, c-Abl, ferroptosis-related pathways, telomerase-associated mechanisms, and circadian regulators, to understand how reproductive tissues respond to physiological and pathological stress.
Yeditepe University
Istanbul, Türkiye
Scientific Publications
Latest scientific articles and research papers contributed by our team to the global literature.
2026
The Role of the Hippo Signaling Pathway in 7,12‐Dimethylbenz(a)anthracene (DMBA)‐Induced Follicular Depletion
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Last Updated: June 13, 2026
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Last Updated: June 13, 2026
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Last Updated: June 13, 2026
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Inquiries
Last Updated: June 13, 2026
For academic collaborations, scientific consultancy, or inquiries regarding the Yucar Lab Summer Research Program, please reach out to us through the following channels:
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